Down-regulation of the Nucleotide Excision Repair gene <it>XPG </it>as a new mechanism of drug resistance in human and murine cancer cells

<p>Abstract</p> <p>Background</p> <p>Drug resistance is one of the major obstacles limiting the activity of anticancer agents. Activation of DNA repair mechanism often accounts for increase resistance to cancer chemotherapy.</p> <p>Results</p> <p>...

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Bibliographic Details
Main Authors: Geroni Cristina, Caiola Elisa, Ganzinelli Monica, Marabese Mirko, Sabatino Maria, Broggini Massimo
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/259