Lipopolysaccharide-Induced CXCL10 mRNA Level and Six Stimulant-mRNA Combinations in Whole Blood: Novel Biomarkers for Bortezomib Responses Obtained from a Prospective Multicenter Trial for Patients with Multiple Myeloma.

Lipopolysaccharide-Induced CXCL10 mRNA Level and Six Stimulant-mRNA Combinations in Whole Blood: Novel Biomarkers for Bortezomib Responses Obtained from a Prospective Multicenter Trial for Patients with Multiple Myeloma.

To identify predictive biomarkers for clinical responses to bortezomib treatment, 0.06 mL of each whole blood without any cell separation procedures was stimulated ex vivo using five agents, and eight mRNAs were quantified. In six centers, heparinized peripheral blood was prospectively obtained from...

Full description

Bibliographic Details
Main Authors: Takashi Watanabe, Masato Mitsuhashi, Morihiko Sagawa, Masaki Ri, Kenshi Suzuki, Masahiro Abe, Ken Ohmachi, Yasunori Nakagawa, Shingen Nakamura, Mizuki Chosa, Shinsuke Iida, Masahiro Kizaki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4482752?pdf=render

Internet

http://europepmc.org/articles/PMC4482752?pdf=render

Similar Items