Predictive SNPs for β0-thalassemia/HbE disease severity

Abstract β-Thalassemia/HbE disease has a wide spectrum of clinical phenotypes ranging from asymptomatic to dependent on regular blood transfusions. Ability to predict disease severity is helpful for clinical management and treatment decision making. A thalassemia severity score has been developed fr...

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Bibliographic Details
Main Authors: Thongperm Munkongdee, Sissades Tongsima, Chumpol Ngamphiw, Pongsakorn Wangkumhang, Chayanon Peerapittayamongkol, Hafizah Binti Hashim, Suthat Fucharoen, Saovaros Svasti
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89641-2