Pyridoxine Deficiency Exacerbates Neuronal Damage after Ischemia by Increasing Oxidative Stress and Reduces Proliferating Cells and Neuroblasts in the Gerbil Hippocampus

Pyridoxine Deficiency Exacerbates Neuronal Damage after Ischemia by Increasing Oxidative Stress and Reduces Proliferating Cells and Neuroblasts in the Gerbil Hippocampus

We investigated the effects of pyridoxine deficiency on ischemic neuronal death in the hippocampus of gerbil (<i>n</i> = 5 per group). Serum pyridoxal 5′-phosphate levels were significantly decreased in Pyridoxine-deficient diet (PDD)-fed gerbils, while homocysteine levels were significa...

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Bibliographic Details
Main Authors: Hyo Young Jung, Woosuk Kim, Kyu Ri Hahn, Min Soo Kang, Tae Hyeong Kim, Hyun Jung Kwon, Sung Min Nam, Jin Young Chung, Jung Hoon Choi, Yeo Sung Yoon, Dae Won Kim, Dae Young Yoo, In Koo Hwang
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
pyridoxine deficiency
ischemia
gerbil
homocysteine
cell death
glia
Online Access:https://www.mdpi.com/1422-0067/21/15/5551

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https://www.mdpi.com/1422-0067/21/15/5551

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