Expansion of CD4<sup>+</sup>CD25<sup>+ </sup>helper T cells without regulatory function in smoking and COPD

Expansion of CD4<sup>+</sup>CD25<sup>+ </sup>helper T cells without regulatory function in smoking and COPD

<p>Abstract</p> <p>Background</p> <p>Regulatory T cells have been implicated in the pathogenesis of COPD by the increased expression of CD25 on helper T cells along with enhanced intracellular expression of FoxP3 and low/absent CD127 expression on the cell surface.</...

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Bibliographic Details
Main Authors: Bucht Anders, Behndig Annelie F, Pourazar Jamshid, Roos-Engstrand Ester, Blomberg Anders
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Respiratory Research
Subjects:
Bronchoalveolar lavage
BAL
CD25<sup>bright</sup>
CD127
FoxP3
lymphocyte subsets
Online Access:http://respiratory-research.com/content/12/1/74

Internet

http://respiratory-research.com/content/12/1/74

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