Increased lipid rafts and accelerated lipopolysaccharide-induced tumor necrosis factor-α secretion in Abca1-deficient macrophagess⃞

Increased lipid rafts and accelerated lipopolysaccharide-induced tumor necrosis factor-α secretion in Abca1-deficient macrophagess⃞

Lipid rafts on the cell surface are believed to be very important as platforms for various cellular functions. The aim of this study was to know whether defective lipid efflux may influence lipid rafts on the cell surface and their related cellular functions. We investigated macrophages with defecti...

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Bibliographic Details
Main Authors: Masahiro Koseki, Ken-ichi Hirano, Daisaku Masuda, Chiaki Ikegami, Masaki Tanaka, Akemi Ota, Jose C. Sandoval, Yumiko Nakagawa-Toyama, Satoshi B. Sato, Toshihide Kobayashi, Yukiko Shimada, Yoshiko Ohno-Iwashita, Fumihiko Matsuura, Iichiro Shimomura, Shizuya Yamashita
Format: Article
Language:English
Published: Elsevier 2007-02-01
Series:Journal of Lipid Research
Subjects:
ATP binding cassette transporter A1
biotinylated and protease (subtilisin Carlsberg)-nicked derivative of θ-toxin
cholesterol efflux
lipid rafts
polyethylene glycol-derived cholesterol
tumor necrosis factor-α
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752043665X

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http://www.sciencedirect.com/science/article/pii/S002222752043665X

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