Chronomodulated Nifedipine Supports Concurrent Glimepiride Administration with Subsequent Amelioration of Retinopathy and Peripheral Neuropathy in Diabetic Rats

This study investigated effect of chronomodulated nifedipine on two microvascular complications in glimepiride-treated diabetic rats for 21 days. Groups 1 and 2 were non-diabetic and diabetic controls respectively, receiving 1 ml/kg PEG+H2O. Groups 3-5 were diabetic, receiving 10 mg/kg glimepiride a...

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Bibliographic Details
Main Authors: Michael Ikechukwu Oraebosi, Temidayo Olutoyin Olurishe, Lydia Ojonemile Ayanwuyi
Format: Article
Language:English
Published: KenzPub 2019-10-01
Series:Egyptian Journal of Basic and Clinical Pharmacology
Subjects:
Online Access:https://www.kenzpub.com/journals/ejbcp/2019/101437/