Lymphedema alters lipolytic, lipogenic, immune and angiogenic properties of adipose tissue: a hypothesis-generating study in breast cancer survivors

Abstract Later stages of secondary lymphedema are associated with the massive deposition of adipose tissue (AT). The factors driving lymphedema-associated AT (LAT) expansion in humans remain rather elusive. We hypothesized that LAT expansion could be based on alterations of metabolic, adipogenic, im...

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Bibliographic Details
Main Authors: Michal Koc, Martin Wald, Zuzana Varaliová, Barbora Ondrůjová, Terezie Čížková, Milan Brychta, Jana Kračmerová, Lenka Beranová, Jan Pala, Veronika Šrámková, Michaela Šiklová, Jan Gojda, Lenka Rossmeislová
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87494-3