A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approach.

The identification of MHC class II restricted peptide epitopes is an important goal in immunological research. A number of computational tools have been developed for this purpose, but there is a lack of large-scale systematic evaluation of their performance. Herein, we used a comprehensive dataset...

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Bibliographic Details
Main Authors: Peng Wang, John Sidney, Courtney Dow, Bianca Mothé, Alessandro Sette, Bjoern Peters
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2267221?pdf=render