PHIP hyperpolarized [1-13C]pyruvate and [1-13C]acetate esters via PH-INEPT polarization transfer monitored by 13C NMR and MRI

Abstract Parahydrogen-induced polarization of 13C nuclei by side-arm hydrogenation (PHIP-SAH) for [1-13C]acetate and [1-13C]pyruvate esters with application of PH-INEPT-type pulse sequences for 1H to 13C polarization transfer is reported, and its efficiency is compared with that of polarization tran...

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Bibliographic Details
Main Authors: Alexandra Svyatova, Vitaly P. Kozinenko, Nikita V. Chukanov, Dudari B. Burueva, Eduard Y. Chekmenev, Yu-Wen Chen, Dennis W. Hwang, Kirill V. Kovtunov, Igor V. Koptyug
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85136-2