Ontogeny Related Changes in the Pediatric Liver Metabolome

Background: A major challenge in implementing personalized medicine in pediatrics is identifying appropriate drug dosages for children. The majority of drug dosing studies have been based on adult populations, often with modification of the dosing for children based on size and weight. However, the...

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Bibliographic Details
Main Authors: Christopher M. Wilson, Qian Li, Roger Gaedigk, Charlie Bi, Saskia N. de Wildt, J. Steven Leeder, Brooke L. Fridley
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fped.2020.00549/full