Identifying novel drug indications through automated reasoning.

With the large amount of pharmacological and biological knowledge available in literature, finding novel drug indications for existing drugs using in silico approaches has become increasingly feasible. Typical literature-based approaches generate new hypotheses in the form of protein-protein interac...

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Bibliographic Details
Main Authors: Luis Tari, Nguyen Vo, Shanshan Liang, Jagruti Patel, Chitta Baral, James Cai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3402456?pdf=render