A seed-extended algorithm for detecting protein complexes based on density and modularity with topological structure and GO annotations

Abstract Background The detection of protein complexes is of great significance for researching mechanisms underlying complex diseases and developing new drugs. Thus, various computational algorithms have been proposed for protein complex detection. However, most of these methods are based on only t...

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Bibliographic Details
Main Authors: Rongquan Wang, Caixia Wang, Liyan Sun, Guixia Liu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-019-5956-y