A seed-extended algorithm for detecting protein complexes based on density and modularity with topological structure and GO annotations
Abstract Background The detection of protein complexes is of great significance for researching mechanisms underlying complex diseases and developing new drugs. Thus, various computational algorithms have been proposed for protein complex detection. However, most of these methods are based on only t...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-08-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12864-019-5956-y |