Aptamer-miRNA-212 Conjugate Sensitizes NSCLC Cells to TRAIL

Aptamer-miRNA-212 Conjugate Sensitizes NSCLC Cells to TRAIL

TNF-related apoptosis-inducing ligand (TRAIL) is a promising antitumor agent for its remarkable ability to selectively induce apoptosis in cancer cells, without affecting the viability of healthy bystander cells. The TRAIL tumor suppressor pathway is deregulated in many human malignancies including...

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Bibliographic Details
Main Authors: Margherita Iaboni, Valentina Russo, Raffaela Fontanella, Giuseppina Roscigno, Danilo Fiore, Elvira Donnarumma, Carla Lucia Esposito, Cristina Quintavalle, Paloma H Giangrande, Vittorio de Franciscis, Gerolama Condorelli
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
aptamer
microRNA
non-small cell lung cancer
TNF-related apoptosis-inducing ligand
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253117300835

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http://www.sciencedirect.com/science/article/pii/S2162253117300835

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