Immunization of mice with soluble lysate of interferon gamma expressing Plasmodium berghei ANKA induces high IFN-γ production

Immunization of mice with soluble lysate of interferon gamma expressing Plasmodium berghei ANKA induces high IFN-γ production

Abstract Background Efforts in search of lasting malaria vaccine have led to the development of transgenic rodent malaria parasites. As a result, wild type Plasmodium berghei ANKA (WTPbA) has recently been transformed to express mouse interferon gamma (mIFN-γ). The immunomodulatory effect of this tr...

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Bibliographic Details
Main Authors: Ebenezer Taylor, Faith Onditi, Naomi Maina, Hastings Ozwara
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Tropical Diseases, Travel Medicine and Vaccines
Subjects:
Immunization
Interferon gamma
Malaria
Plasmodium berghei
Mouse IFN-γ expressing PbA
Online Access:http://link.springer.com/article/10.1186/s40794-017-0053-1

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http://link.springer.com/article/10.1186/s40794-017-0053-1

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