Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system

Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system

Kostrzewski et al. introduce an in vitro microphysiological model of non-alcoholic steatohepatitis (NASH), consisting of co-cultured primary human liver cells. The authors characterised the transcriptomic, inflammatory and fibrotic phenotype of the model and show that major features of NASH can be r...

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Bibliographic Details
Main Authors: Tomasz Kostrzewski, Sophie Snow, Anya Lindström Battle, Samantha Peel, Zahida Ahmad, Jayati Basak, Manasa Surakala, Aurelie Bornot, Julia Lindgren, Maria Ryaboshapkina, Maryam Clausen, Daniel Lindén, Christian Maass, Lucy May Young, Adam Corrigan, Lorna Ewart, David Hughes
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02616-x

Internet

https://doi.org/10.1038/s42003-021-02616-x

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