A Viperin Mutant Bearing the K358R Substitution Lost its Anti-ZIKA Virus Activity

Interferon-induced viperin (VP) was identified as playing an important role in the innate immune response against Zika virus (ZIKV). The 361 amino acid long human VP protein comprises of a highly conserved C-terminal region, which has been associated with VP antiviral properties against ZIKV. In the...

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Bibliographic Details
Main Authors: Bénédicte Vanwalscappel, Gilles Gadea, Philippe Desprès
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
ISG
Online Access:https://www.mdpi.com/1422-0067/20/7/1574