Nitric Oxide Synthase Type III Overexpression By Gene Therapy Exerts Antitumoral Activity In Mouse Hepatocellular Carcinoma

Nitric Oxide Synthase Type III Overexpression By Gene Therapy Exerts Antitumoral Activity In Mouse Hepatocellular Carcinoma

Hepatocellular carcinoma develops in cirrhotic liver. The nitric oxide (NO) synthase type III (NOS-3) overexpression induces cell death in hepatoma cells. The study developed gene therapy designed to specifically overexpress NOS-3 in cultured hepatoma cells, and in tumors derived from orthotopically...

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Bibliographic Details
Main Authors: Raúl González, Ángel J. De la Rosa, Santiago Romero-Brufau, Lydia Barrera-Pulido, Francisco Gallardo-Chamizo, Sheila Pereira, Luís M. Marín, José M. Álamo, Ángeles Rodríguez-Hernández, Francisco J. Padillo, Jordi Muntané
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231715001433

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http://www.sciencedirect.com/science/article/pii/S2213231715001433

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