SIRT1 in the Development and Treatment of Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related death worldwide. Current treatment options for inoperable HCCs have decreased therapeutic efficacy and are associated with systemic toxicity and chemoresistance. Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide...

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Bibliographic Details
Main Authors: Marius Farcas, Andrei-Alexandru Gavrea, Diana Gulei, Calin Ionescu, Alexandru Irimie, Cristina S. Catana, Ioana Berindan-Neagoe
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Nutrition
Subjects:
HCC
Online Access:https://www.frontiersin.org/article/10.3389/fnut.2019.00148/full