Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H2S system: Role of oxidative stress and endoplasmic reticulum stress

Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H2S system: Role of oxidative stress and endoplasmic reticulum stress

Neonatal hypoxic-ischemic (HI) injury is a major cause of neonatal death and neurological dysfunction. H2S has been shown to protect against hypoxia-induced injury and apoptosis of neurons. L-Cysteine is catalyzed by cystathionine-β-synthase (CBS) in the brain and sequentially produces endogenous H2...

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Bibliographic Details
Main Authors: Song Liu, Danqing Xin, Lingxiao Wang, Tiantian Zhang, Xuemei Bai, Tong Li, Yunkai Xie, Hao Xue, Shishi Bo, Dexiang Liu, Zhen Wang
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Redox Biology
Subjects:
L-Cysteine
H2S
Hypoxia-ischemia
Oxidative stress
Endoplasmic reticulum stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717303336

Internet

http://www.sciencedirect.com/science/article/pii/S2213231717303336

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