Double N-arylation reaction of polyhalogenated 4,4’-bipyridines. Expedious synthesis of functionalized 2,7-diazacarbazoles

Double N-arylation reaction of polyhalogenated 4,4’-bipyridines. Expedious synthesis of functionalized 2,7-diazacarbazoles

Unusual 2,7-diazacarbazoles were prepared in one step from readily available tetra-halogenated 4,4’-bipyridines by using a double N-arylation reaction in the presence of the Pd–XPhos catalyst system. Moderate to good yields were obtained in this site-selective Buchwald–Hartwig double amination. The...

Full description

Bibliographic Details
Main Authors: Mohamed Abboud, Emmanuel Aubert, Victor Mamane
Format: Article
Language:English
Published: Beilstein-Institut 2012-02-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
4,4’-bipyridine
cross-coupling
crystal packing
diazacarbazole
X-ray diffraction
Online Access:https://doi.org/10.3762/bjoc.8.26

Internet

https://doi.org/10.3762/bjoc.8.26

Similar Items