AHR signaling is induced by infection with coronaviruses

RNA viruses, such as Zika and Dengue, activate the aryl hydrocarbon receptor (AHR) signaling to restrict the antiviral response. Here, the authors report that coronaviruses also activate AHR signaling, potentially allowing them to escape the immune response, and show that AHR antagonism limits SARS-...

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Bibliographic Details
Main Authors: Federico Giovannoni, Zhaorong Li, Federico Remes-Lenicov, María E. Dávola, Mercedes Elizalde, Ana Paletta, Ali A. Ashkar, Karen L. Mossman, Andrea V. Dugour, Juan M. Figueroa, Andrea A. Barquero, Ana Ceballos, Cybele C. Garcia, Francisco J. Quintana
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25412-x