Structural and biophysical characterization of the tandem substrate-binding domains of the ABC importer GlnPQ

Structural and biophysical characterization of the tandem substrate-binding domains of the ABC importer GlnPQ

The ATP-binding cassette transporter GlnPQ is an essential uptake system that transports glutamine, glutamic acid and asparagine in Gram-positive bacteria. It features two extra-cytoplasmic substrate-binding domains (SBDs) that are linked in tandem to the transmembrane domain of the transporter. The...

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Bibliographic Details
Main Authors: Evelyn Ploetz, Gea K. Schuurman-Wolters, Niels Zijlstra, Amarins W. Jager, Douglas A. Griffith, Albert Guskov, Giorgos Gouridis, Bert Poolman, Thorben Cordes
Format: Article
Language:English
Published: The Royal Society 2021-04-01
Series:Open Biology
Subjects:
ABC transporter
substrate-binding protein
Förster resonance energy transfer
protein-induced fluorescence enhancement
single-molecule spectroscopy
tandem substrate-binding domains
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.200406

Internet

https://royalsocietypublishing.org/doi/10.1098/rsob.200406

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