First-In-Human Study in Cancer Patients Establishing the Feasibility of Oxygen Measurements in Tumors Using Electron Paramagnetic Resonance With the OxyChip

First-In-Human Study in Cancer Patients Establishing the Feasibility of Oxygen Measurements in Tumors Using Electron Paramagnetic Resonance With the OxyChip

ObjectiveThe overall objective of this clinical study was to validate an implantable oxygen sensor, called the ‘OxyChip’, as a clinically feasible technology that would allow individualized tumor-oxygen assessments in cancer patients prior to and during hypoxia-modification interventions such as hyp...

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Main Authors: Philip E. Schaner, Benjamin B. Williams, Eunice Y. Chen, Jason R. Pettus, Wilson A. Schreiber, Maciej M. Kmiec, Lesley A. Jarvis, David A. Pastel, Rebecca A. Zuurbier, Roberta M. DiFlorio-Alexander, Joseph A. Paydarfar, Benoit J. Gosselin, Richard J. Barth, Kari M. Rosenkranz, Sergey V. Petryakov, Huagang Hou, Dan Tse, Alexandre Pletnev, Ann Barry Flood, Victoria A. Wood, Kendra A. Hebert, Robyn E. Mosher, Eugene Demidenko, Harold M. Swartz, Periannan Kuppusamy
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
OxyChip
oximetry
EPR
tumor
radiation
chemotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.743256/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.743256/full

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