Depletion of Paraspeckle Protein 1 Enhances Methyl Methanesulfonate-Induced Apoptosis through Mitotic Catastrophe.

Depletion of Paraspeckle Protein 1 Enhances Methyl Methanesulfonate-Induced Apoptosis through Mitotic Catastrophe.

Previously, we have shown that paraspeckle protein 1 (PSPC1), a protein component of paraspeckles that was involved in cisplatin-induced DNA damage response (DDR), probably functions at the G1/S checkpoint. In the current study, we further examined the role of PSPC1 in another DNA-damaging agent, me...

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Bibliographic Details
Main Authors: Xiangjing Gao, Guanglin Zhang, Shigang Shan, Yunlong Shang, Linfeng Chi, Hongjuan Li, Yifei Cao, Xinqiang Zhu, Meibian Zhang, Jun Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4718682?pdf=render

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http://europepmc.org/articles/PMC4718682?pdf=render

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