Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo.

Notch signalling is a fundamental pathway that shapes the developing embryo and sustains adult tissues by direct communication between ligand and receptor molecules on adjacent cells. Among the ligands are two Delta paralogues, DLL1 and DLL4, that are conserved in mammals and share a similar structu...

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Bibliographic Details
Main Authors: Kristina Preuße, Lena Tveriakhina, Karin Schuster-Gossler, Cláudia Gaspar, Alexandra Isabel Rosa, Domingos Henrique, Achim Gossler, Michael Stauber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4482573?pdf=render