CHANGES IN THE MGMT GENE EXPRESSION IN PATIENTS WITH PRIMARY GLIOBLASTOMA AFTER RELAPSE. INFLUENCE OF CLINICAL CHARACTERISTICS AND MGMT EXPRESSION ON SURVIVAL OF PATIENTS

CHANGES IN THE MGMT GENE EXPRESSION IN PATIENTS WITH PRIMARY GLIOBLASTOMA AFTER RELAPSE. INFLUENCE OF CLINICAL CHARACTERISTICS AND MGMT EXPRESSION ON SURVIVAL OF PATIENTS

Background. Over the past 10–15 years, there has been a clearer understanding of the processes occurring in cells of the primary glioblastoma. However, the change in MGMT gene expression and its role after disease relapse remain understudied. Purpose: to study changes in MGMT gene expression in case...

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Bibliographic Details
Main Authors: M. V. Matsko, S. S. Sklyar, A. Yu. Ulitin, D. E. Matsko, E. N. Imyanitov, A. G. Ievleva, V. I. Ni, N. M. Volkov, A. A. Zrelov, A. O. Baksheeva, D. V. Galkina
Format: Article
Language:Russian
Published: Tomsk National Research Medical Center of the Russian Academy of Sciences 2021-06-01
Series:Sibirskij Onkologičeskij Žurnal
Subjects:
primary glioblastoma
glioblastoma recurrence
mutations idh1/idh2 genes, mgmt gene
temozolomide
progression-free survival
extent of resection
Online Access:https://www.siboncoj.ru/jour/article/view/1802

Internet

https://www.siboncoj.ru/jour/article/view/1802

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