Nonlinear Decoding and Asymmetric Representation of Neuronal Input Information by CaMKIIα and Calcineurin

How information encoded in glutamate release rates at individual synapses is converted into biochemical activation patterns of postsynaptic enzymes remains unexplored. To address this, we developed a dual fluorescence resonance energy transfer (FRET) imaging platform and recorded CaMKIIα and calcin...

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Bibliographic Details
Main Authors: Hajime Fujii, Masatoshi Inoue, Hiroyuki Okuno, Yoshikazu Sano, Sayaka Takemoto-Kimura, Kazuo Kitamura, Masanobu Kano, Haruhiko Bito
Format: Article
Language:English
Published: Elsevier 2013-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713001551