Endotoxin dosage in sepsis

Introduction. Endotoxin, a component of the cell wall of Gram-negative bacteria is a major contributor to the pathogenesis of septic shock and multiple organ failure (MOF). Its entry into the bloodstream stimulates monocytes/macrophages which once activated produce and release cytokines, nitric oxid...

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Bibliographic Details
Main Authors: Vincenzo Rondinelli, Stefania Giglio, Vittorio Focarelli, Raffaele Saraceno, Pasquale Minchella, Maria Gabriella Lepore, Nicola Iiritano, Sandra Castagna, Paolo Opipari, Teresa Alcaro, Antonio Balducci, Rosanna Masciari
Format: Article
Language:English
Published: PAGEPress Publications 2012-03-01
Series:Microbiologia Medica
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Online Access:http://www.pagepressjournals.org/index.php/mm/article/view/2333