Impact and Beneficial Critical Points of Clinical Outcome in Corticosteroid Management of Adult Patients With Sepsis: Meta-Analysis and GRADE Assessment

Impact and Beneficial Critical Points of Clinical Outcome in Corticosteroid Management of Adult Patients With Sepsis: Meta-Analysis and GRADE Assessment

Background: With new randomised pieces of evidence and the latest clinical practice guideline from the BMJ emerging in 2018, an updated analysis of best available evidence on the controversial effects of corticosteroids in sepsis is warranted.Objectives: To comprehensively evaluate whether corticost...

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Bibliographic Details
Main Authors: Lu-Lu Lin, Hui-Yun Gu, Jie Luo, Long Wang, Chao Zhang, Yu-Ming Niu, Hong-Xia Zuo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
sepsis
septic shock
corticosteroids
long course low-dose
28-day mortality
dose-response meta-analysis
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01101/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.01101/full

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