Inhibition of Ocular Aldose Reductase by a New Benzofuroxane Derivative Ameliorates Rat Endotoxic Uveitis

The study investigated the effects of the aldose reductase (AR) inhibitor benzofuroxane derivative 5(6)-(benzo[d]thiazol-2-ylmethoxy) benzofuroxane (herein referred to as BF-5m) on the biochemical and tissue alterations induced by endotoxic uveitis in rats. BF-5m has been administered directly into...

Full description

Bibliographic Details
Main Authors: C. Di Filippo, M. V. Zippo, R. Maisto, M. C. Trotta, D. Siniscalco, B. Ferraro, F. Ferraraccio, C. La Motta, S. Sartini, S. Cosconati, E. Novellino, C. Gesualdo, F. Simonelli, S. Rossi, M. D’Amico
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2014/857958