Changes in positive end-expiratory pressure alter the distribution of ventilation within the lung immediately after birth in newborn rabbits.

Current recommendations suggest the use of positive end-expiratory pressures (PEEP) to assist very preterm infants to develop a functional residual capacity (FRC) and establish gas exchange at birth. However, maintaining a consistent PEEP is difficult and so the lungs are exposed to changing distend...

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Bibliographic Details
Main Authors: Marcus J Kitchen, Melissa L Siew, Megan J Wallace, Andreas Fouras, Robert A Lewis, Naoto Yagi, Kentaro Uesugi, Arjan B Te Pas, Stuart B Hooper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3972143?pdf=render