The analysis of GSTA1 promoter genetic and functional diversity of human populations

Abstract GSTA1 encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. GSTA1 has several functional SNPs within its promoter region that are responsib...

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Bibliographic Details
Main Authors: Vid Mlakar, Patricia Huezo-Diaz Curtis, Marc Armengol, Victor Ythier, Isabelle Dupanloup, Khalil Ben Hassine, Laurence Lesne, Rabih Murr, Simona Jurkovic Mlakar, Tiago Nava, Marc Ansari
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83996-2