Variants in doublecortin- and calmodulin kinase like 1, a gene up-regulated by BDNF, are associated with memory and general cognitive abilities.

Human memory and general cognitive abilities are complex functions of high heritability and wide variability in the population. The brain-derived neurotrophic factor (BDNF) plays an important role in mammalian memory formation.Based on the identification of genes markedly up-regulated during BDNF-in...

Full description

Bibliographic Details
Main Authors: Stéphanie Le Hellard, Bjarte Håvik, Thomas Espeseth, Harald Breilid, Roger Løvlie, Michelle Luciano, Alan J Gow, Sarah E Harris, John M Starr, Karin Wibrand, Astri J Lundervold, David J Porteous, Clive R Bramham, Ian J Deary, Ivar Reinvang, Vidar M Steen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2760101?pdf=render