Multi-Epitope-Based Vaccines for Colon Cancer Treatment and Prevention

Multi-Epitope-Based Vaccines for Colon Cancer Treatment and Prevention

BackgroundOverexpression of nonmutated proteins involved in oncogenesis is a mechanism by which such proteins become immunogenic. We questioned whether overexpressed colorectal cancer associated proteins found at higher incidence and associated with poor prognosis could be effective vaccine antigens...

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Bibliographic Details
Main Authors: Lauren R. Corulli, Denise L. Cecil, Ekram Gad, Marlese Koehnlein, Andrew L. Coveler, Jennifer S. Childs, Ronald A. Lubet, Mary L. Disis
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
immunotherapy
colon cancer
CDC25B
COX2
IFN-gamma
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.729809/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.729809/full

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