Preferential inhibition of adaptive immune system dynamics by glucocorticoids in patients after acute surgical trauma

Preferential inhibition of adaptive immune system dynamics by glucocorticoids in patients after acute surgical trauma

Glucocorticoids (GC) are commonly used to suppress undesirable inflammatory responses. Here the authors show, using hi-dimensional flow cytometry data, that GC treatment following major surgeries alters adaptive immunity without significant modulation of innate immune responses or pain/functional im...

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Bibliographic Details
Main Authors: Edward A. Ganio, Natalie Stanley, Viktoria Lindberg-Larsen, Jakob Einhaus, Amy S. Tsai, Franck Verdonk, Anthony Culos, Sajjad Ghaemi, Kristen K. Rumer, Ina A. Stelzer, Dyani Gaudilliere, Eileen Tsai, Ramin Fallahzadeh, Benjamin Choisy, Henrik Kehlet, Nima Aghaeepour, Martin S. Angst, Brice Gaudilliere
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17565-y

Internet

https://doi.org/10.1038/s41467-020-17565-y

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