Directed synthesis and search of pharmaceutical substances with hypoglycemic activity in the series of 4-aryl-2-hydroxy-4-oxo-2-butenoic acids
The paper deals with directed synthesis and study of hypoglycemic activity of N-heterylamides of 4-aryl-2-hydroxy-4-oxo-2- butenoic and 4-aryl-3-bromo-2, 4-dioxobutanoic acids. Hypoglycemic activity of 28 compounds was under research. Some regularities of the influence of the heterocyclic moiety str...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Siberian State Medical University (Tomsk)
2011-10-01
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| Series: | Bûlleten' Sibirskoj Mediciny |
| Subjects: | |
| Online Access: | https://bulletin.tomsk.ru/jour/article/view/1473 |