Use of Diffusion Spectrum imaging in preliminary longitudinal evaluation of Amyotrophic Lateral Sclerosis: development of an imaging biomarker

Use of Diffusion Spectrum imaging in preliminary longitudinal evaluation of Amyotrophic Lateral Sclerosis: development of an imaging biomarker

Previous diffusion tensor imaging (DTI) studies have shown white matter pathology in ALS, predominantly in the motor pathways. Further these studies have shown that DTI can be used longitudinally to track pathology over time, making white matter pathology a candidate as an outcome measure in future...

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Bibliographic Details
Main Authors: Kumar eAbhinav, Fang-Chang eYeh, Ahmed eEl-Dokla, Lisa M. Ferrando, Yue-Fang eChang, David eLacomis, Robert M. Friedlander, Juan C. Fernandez-Miranda
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Human Neuroscience
Subjects:
Amyotrophic Lateral Sclerosis
Longitudinal
white matter
Diffusion spectrum imaging
motoric
extramotoric
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.00270/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.00270/full

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