Structural characterisation of the nuclear import receptor importin alpha in complex with the bipartite NLS of Prp20.

Structural characterisation of the nuclear import receptor importin alpha in complex with the bipartite NLS of Prp20.

The translocation of macromolecules into the nucleus is a fundamental eukaryotic process, regulating gene expression, cell division and differentiation, but which is impaired in a range of significant diseases including cancer and viral infection. The import of proteins into the nucleus is generally...

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Bibliographic Details
Main Authors: Noelia Roman, Mary Christie, Crystall M D Swarbrick, Bostjan Kobe, Jade K Forwood
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24339986/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24339986/pdf/?tool=EBI

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