Structural characterisation of the nuclear import receptor importin alpha in complex with the bipartite NLS of Prp20.
The translocation of macromolecules into the nucleus is a fundamental eukaryotic process, regulating gene expression, cell division and differentiation, but which is impaired in a range of significant diseases including cancer and viral infection. The import of proteins into the nucleus is generally...
Main Authors: | Noelia Roman, Mary Christie, Crystall M D Swarbrick, Bostjan Kobe, Jade K Forwood |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24339986/pdf/?tool=EBI |
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