ERBB1- and ERBB2-Positive Medullary Thyroid Carcinoma: A Case Report

ERBB1- and ERBB2-Positive Medullary Thyroid Carcinoma: A Case Report

Medullary thyroid carcinomas (MTCs) are rare thyroid tumors occurring in both sporadic and hereditary forms, whose pathogenesis is related to RET proto-oncogene alterations. MTCs originate from parafollicular cells, which produce calcitonin that represents the biochemical activity of MTC. Total thyr...

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Bibliographic Details
Main Authors: Michele Minuto, Emanuela Varaldo, Gianluca Marcocci, Amleto de Santanna, Ermanno Ciccone, Katia Cortese
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Diseases
Subjects:
MTC
calcitonin
parafollicular C cells
secretory granules
immunofluorescence
ultrastructure
transmission electron microscopy
ERBB1
ERBB2
Online Access:http://www.mdpi.com/2079-9721/6/2/25

Internet

http://www.mdpi.com/2079-9721/6/2/25

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