Nuclear factor-κB-dependent epithelial to mesenchymal transition induced by HIF-1α activation in pancreatic cancer cells under hypoxic conditions.

Nuclear factor-κB-dependent epithelial to mesenchymal transition induced by HIF-1α activation in pancreatic cancer cells under hypoxic conditions.

Epithelial to mesenchymal transition (EMT) induced by hypoxia is one of the critical causes of treatment failure in different types of human cancers. NF-κB is closely involved in the progression of EMT. Compared with HIF-1α, the correlation between NF-κB and EMT during hypoxia has been less studied,...

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Bibliographic Details
Main Authors: Zhuo-Xin Cheng, Bei Sun, Shuang-Jia Wang, Yue Gao, Ying-Mei Zhang, Hao-Xin Zhou, Guang Jia, Yong-Wei Wang, Rui Kong, Shang-Ha Pan, Dong-Bo Xue, Hong-Chi Jiang, Xue-Wei Bai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3161785?pdf=render

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http://europepmc.org/articles/PMC3161785?pdf=render

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