Altered Plasma Acylcarnitines and Amino Acids Profile in Spinocerebellar Ataxia Type 7

Altered Plasma Acylcarnitines and Amino Acids Profile in Spinocerebellar Ataxia Type 7

Spinocerebellar ataxia type 7 (SCA7), a neurodegenerative disease characterized by cerebellar ataxia and retinal degeneration, is caused by an abnormal CAG repeat expansion in the <i>ATXN7</i> gene coding region. The onset and severity of SCA7 are highly variable between patients, thus i...

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Bibliographic Details
Main Authors: Rafael Nambo-Venegas, Claudia Valdez-Vargas, Bulmaro Cisneros, Berenice Palacios-González, Marcela Vela-Amieva, Isabel Ibarra-González, César M. Cerecedo-Zapata, Emilio Martínez-Cruz, Hernán Cortés, Juan P. Reyes-Grajeda, Jonathan J. Magaña
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Biomolecules
Subjects:
spinocerebellar ataxia 7
cag repeats
polyglutamine disease
metabolomics
biomarkers
mitochondrial disease
metabolic pathways
Online Access:https://www.mdpi.com/2218-273X/10/3/390

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https://www.mdpi.com/2218-273X/10/3/390

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