Effect of Oxaliplatin on sperm parameters of 60 days old offspring during pre-pregnancy, pregnancy and lactation period in mice

Background and Objective: Oxaliplatin is the main agent used in the treatment of colorectal cancers. Oxaliplatin inhibits DNA replication and transcription and to induce apoptosis or necrosis in cancer cells and rapidly dividing cell lines. This study was designed to determine the effect of Oxalipla...

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Bibliographic Details
Main Authors: Moslem Dahmardeh, Javad Sadeghinezhad, Zahra Tootian, Mojdeh Salehnia
Format: Article
Language:fas
Published: Golestan University of Medical Sciences 2020-04-01
Series:مجله دانشگاه علوم پزشکی گرگان
Subjects:
Online Access:http://goums.ac.ir/journal/article-1-3509-en.html