Analysis of Chromosomal Copy Number in First-Trimester Pregnancy Loss Using Next-Generation Sequencing

Analysis of Chromosomal Copy Number in First-Trimester Pregnancy Loss Using Next-Generation Sequencing

Embryonic chromosomal abnormality is one of the significant causative factors of early pregnancy loss. Our goal was to evaluate the clinical utility of next-generation sequencing (NGS) technology in identifying chromosomal anomalies associated with first-trimester pregnancy loss. In addition, we att...

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Bibliographic Details
Main Authors: Lei Fan, Jianli Wu, Yuanyuan Wu, Xinwei Shi, Xing Xin, Shufang Li, Wanjiang Zeng, Dongrui Deng, Ling Feng, Suhua Chen, Juan Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Genetics
Subjects:
first-trimester pregnancy loss
chorionic villi
next generation sequencing
fetal chromosomal abnormality
copy number variation
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.545856/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2020.545856/full

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