Local inflammation induces complement crosstalk which amplifies the antimicrobial response.

By eliciting inflammatory responses, the human immunosurveillance system notably combats invading pathogens, during which acute phase proteins (CRP and cytokines) are elevated markedly. However, the Pseudomonas aeruginosa is a persistent opportunistic pathogen prevalent at the site of local inflamma...

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Bibliographic Details
Main Authors: Jing Zhang, Jingyun Koh, Jinhua Lu, Steffen Thiel, Benjamin S H Leong, Sunil Sethi, Cynthia Y X He, Bow Ho, Jeak L Ding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2629585?pdf=render