Apoptotic Cells for Therapeutic Use in Cytokine Storm Associated With Sepsis– A Phase Ib Clinical Trial

Apoptotic Cells for Therapeutic Use in Cytokine Storm Associated With Sepsis– A Phase Ib Clinical Trial

BackgroundSepsis has no proven specific pharmacologic treatment and reported mortality ranges from 30%–45%. The primary aim of this phase IB study was to determine the safety profile of Allocetra™-OTS (early apoptotic cell) infusion in subjects presenting to the emergency room with sepsis. The secon...

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Bibliographic Details
Main Authors: Peter Vernon van Heerden, Avraham Abutbul, Sigal Sviri, Eitan Zlotnick, Ahmad Nama, Sebastian Zimro, Raja el-Amore, Yehudit Shabat, Barak Reicher, Batla Falah, Dror Mevorach
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
sepsis
Inflammation
pneumonia
apoptotic cells
cell therapeutics
cytokine storm
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.718191/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.718191/full

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