Embryonic Hematopoietic Progenitor Cells Reside in Muscle before Bone Marrow Hematopoiesis.

In mice, hematopoietic cells home to bone marrow from fetal liver prenatally. To elucidate mechanisms underlying homing, we performed immunohistochemistry with the hematopoietic cell marker c-Kit, and observed c-Kit(+) cells localized inside muscle surrounding bone after 14.5 days post coitum. Flow...

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Bibliographic Details
Main Authors: Yuka Tanaka, Tomoko Inoue-Yokoo, Kasem Kulkeaw, Chiyo Yanagi-Mizuochi, Senji Shirasawa, Yoichi Nakanishi, Daisuke Sugiyama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4577119?pdf=render