Transcription factor-based gene therapy to treat glioblastoma through direct neuronal conversion

Transcription factor-based gene therapy to treat glioblastoma through direct neuronal conversion

Objective: Glioblastoma (GBM) is the most prevalent and aggressive adult primary cancer in the central nervous system. Therapeutic approaches for GBM treatment are under intense investigation, including the use of emerging immunotherapies. Here, we propose an alternative approach to treat GBM throug...

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Bibliographic Details
Main Authors: Xin Wang, Zifei Pei, Aasma Hossain, Yuting Bai, Gong Chen
Format: Article
Language:English
Published: China Anti-Cancer Association 2021-08-01
Series:Cancer Biology & Medicine
Subjects:
glioblastoma
neuronal conversion
transcription factors
neurod1
neurogenin-2
ascl1
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1823

Internet

http://www.cancerbiomed.org/index.php/cocr/article/view/1823

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