Docosahexaenoic acid ameliorates palmitate-induced lipid accumulation and inflammation through repressing NLRC4 inflammasome activation in HepG2 cells

Docosahexaenoic acid ameliorates palmitate-induced lipid accumulation and inflammation through repressing NLRC4 inflammasome activation in HepG2 cells

<p>Abstract</p> <p>Background</p> <p>N-3 polyunsaturated fatty acids, such as docosahexaenoic acid (DHA; 22:6n-3), has clinical significance in the prevention and reversal of nonalcoholic steatohepatitis (NASH). However, the precious mechanism underlying remains unclear...

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Bibliographic Details
Main Authors: Luo Xiaoqin, Yang Yan, Shen Tianran, Tang Xilan, Xiao Yunjun, Zou Tangbin, Xia Min, Ling Wenhua
Format: Article
Language:English
Published: BMC 2012-04-01
Series:Nutrition & Metabolism
Subjects:
Docosahexaenoic acid
Inflammation
Lipid accumulation
Nonalcoholic steatohepatitis
NLRC4 inflammasome
Palmitate
Online Access:http://www.nutritionandmetabolism.com/content/9/1/34

Internet

http://www.nutritionandmetabolism.com/content/9/1/34

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